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A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties.
Dooley K, McConnell RE, Xu K, Lewis ND, Haupt S, Youniss MR, Martin S, Sia CL, McCoy C, Moniz RJ, Burenkova O, Sanchez-Salazar J, Jang SC, Choi B, Harrison RA, Houde D, Burzyn D, Leng C, Kirwin K, Ross NL, Finn JD, Gaidukov L, Economides KD, Estes S, Thornton JE, Kulman JD, Sathyanarayanan S, Williams DE. Dooley K, et al. Among authors: ross nl. Mol Ther. 2021 May 5;29(5):1729-1743. doi: 10.1016/j.ymthe.2021.01.020. Epub 2021 Jan 21. Mol Ther. 2021. PMID: 33484965 Free PMC article.
ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance.
Jang SC, Economides KD, Moniz RJ, Sia CL, Lewis N, McCoy C, Zi T, Zhang K, Harrison RA, Lim J, Dey J, Grenley M, Kirwin K, Ross NL, Bourdeau R, Villiger-Oberbek A, Estes S, Xu K, Sanchez-Salazar J, Dooley K, Dahlberg WK, Williams DE, Sathyanarayanan S. Jang SC, et al. Among authors: ross nl. Commun Biol. 2021 Apr 22;4(1):497. doi: 10.1038/s42003-021-02004-5. Commun Biol. 2021. PMID: 33888863 Free PMC article.